http://www.intox.org/databank/documents/treat/treate/trt44_e.htm(from lexapro.com)
What other drugs will affect Lexapro?
• Talk to your doctor before taking any medicine for pain, arthritis, fever, or swelling. This includes aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve, Naprosyn), diclofenac (Voltaren), indomethacin, piroxicam (Feldene), nabumetone (Relafen), etodolac (Lodine), and others. Taking any of these drugs with Lexapro may cause you to bruise or bleed easily.
• Before taking Lexapro, tell your doctor if you are using any of the following medicines:
· carbamazepine (Tegretol);
· cimetidine (Tagamet);
· lithium (Lithobid, Eskalith);
· a
http://www.drugs.com/lexapro.html blood thinner such as warfarin (Coumadin);
· any other antidepressants such as amitriptyline (Elavil), citalopram (Celexa), fluoxetine (Prozac, Sarafem), fluvoxamine (Luvox), imipramine (Tofranil), nortriptyline (Pamelor), paroxetine (Paxil), or sertraline (Zoloft); or
· almotriptan (Axert), frovatriptan (Frova), sumatriptan (Imitrex), naratriptan (Amerge), rizatriptan (Maxalt), or zolmitriptan (Zomig).
• If you are using any of these drugs, you may not be able to use Lexapro, or you may need dosage adjustments or special tests during treatment.
• There may be other drugs not listed that can affect Lexapro. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.
(from drug.com)
Serotonin Syndrome
http://www.antidepressantsfacts.com/micromedex-serotonin-syndrome.htmSerotonin Syndrome is a hyperserotonergic state which is a very dangerous and a potentially fatal side effect of serotonergic enhancing drugs which can have multiple psychiatric and non-psychiatric symptoms. This is a toxic condition which requires heightened clinical awareness in order to prevent, recognize, and treat the condition promptly. Promptness is vital because, as we just mentioned, the serotonin syndrome can be fatal and death from this side effect can come very rapidly. This syndrome is a toxic hyperserotonergic state whose rate of incidence is unknown, but is on the rise. This disorder, brought on by excessive levels of serotonin, is difficult to distinguish from the neuroleptic malignant syndrome because the symptoms are so similar. The neuroleptic malignant syndrome is a serious condition brought on by the use of the neuroleptic drugs.
Source: Prozac: Panacea or Pandora? by Dr Ann Blake Tracy
http://members.aol.com/atracyphd/syndrome.htm The Serotonin Syndrome is a potentially lethal condition caused by excessive serotonergic activity and is diagnosed by the presence of at least 3 of 10 symptoms: mental status changes (confusion, hypomania), agitation, myoclonus, hyperreflexia, diaphoresis, shivering, tremor, diarrhea, incoordination, and fever.
Source: Journal of Clinical Psychiatry
Symptoms: euphoria, drowsiness, sustained rapid eye movement, overreaction of the reflexes, rapid muscle contraction and relaxation in the ankle causing abnormal movements of the foot, clumsiness, restlessness, feeling drunk and dizzy, muscle contraction and relaxation in the jaw, sweating, intoxication, muscle twitching, rigidity, high body temperature, mental status changes were frequent (including confusion and hypomania - a "happy drunk" state), shivering, diarrhea, loss of consciousness and death.
Source: American Journal of Psychiatry, June 1991 "The Serotonin Syndrome"
